Hydrogel-Based Drug Delivery System; a Type of Drug Delivery System Used In Many Branches of Medicine

 

Hydrogel-Based Drug Delivery System

The hydrogel-based drug delivery system acts as a controlled drug delivery system to deliver a specific drug for a predetermined period of time. Hydrogels are often used as drug delivery systems because of their high compatibility with living tissues and the property to preserve embedded proteins. Hydrogels are widely used in experimental medicine and clinical practice for various applications, such as regenerative medicine, tissue engineering, diagnostics, cellular immobilization, and biomolecule or cell separation, among others.

Hydrogel-Based Drug Delivery System can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents. The benefits of hydrogel-based drug delivery can be largely pharmacokinetic, particularly as a depot formulation is created whereby the medicine is slowly depleted, maintaining a high local concentration of the drug in the surrounding tissue over an extended period of time, although they can also be used for systemic delivery.

Hydrogel-Based Drug Delivery System is a particularly appealing type of drug delivery system and has been used in several branches of medicine, such as cardiology, immunology, wound healing, oncology, and pain management. Drug delivery is the technology used to present the drug to the desired body site for drug release and absorption, or the subsequent transport of the active ingredients across the biological membranes to the site of action. The controlled delivery of drugs can be effectively obtained using systems based on hydrogels.

Hydrogels are one of the upcoming classes of polymer-based systems that embrace numerous biomedical and pharmaceutical applications. Thus, with the increasing application of Hydrogel-Based Drug Delivery System to treat various disorders, the use of hydrogel-based drug delivery systems is also increasing with a rapid pace. For example, in April 2021, scientists from Japan developed novel hydrogels to effectively deliver drugs to tumor sites in response to temperature and pH changes in the tumor microenvironment, offering hope for effective cancer treatment.

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