What Are Cord Blood Banking Services And How They Can Help Save Lives
Overview of Cord Blood Banking
There are several benefits to Cord
Blood Banking Services for potential future use by the donor or their
family members. First, cord blood contains stem cells that can treat over 80
known diseases right now including conditions like leukemia, lymphoma, some
inherited metabolic disorders, and genetic diseases. Second, cord blood is a
safe source of stem cells compared to bone marrow donations which require
general anesthesia and surgery to collect. Cord blood collection after delivery
is also painless and poses no risk to the mother and baby. Third, cord blood is
often a better tissue match for family members than unrelated donors. This
increases the chances of a successful transplant if needed.
Public vs Private Cord Blood Banking
There are two main types of cord blood banking options - public banking and
private banking. Cord blood collected and stored through public banks is made
available for any patient who needs it through a match in a database. Families
do not own it but their donation helps others in need. Private cord blood banks
allow families to bank and store cord blood for exclusive use by the donor or
immediate family members. If the stem cells are needed years later for any
family member, they are available through the private bank where they were
originally stored and preserved. However, private banking does involve initial
and annual storage fees while public banking is free but only allows use by
patients who find a match.
Processing and Storage of Cord Blood
After obtaining consent from parents during delivery, the umbilical cord is
clamped and blood is drained from the placenta into a collection bag containing
anticoagulant. The cord blood is then transported to a processing lab where it
is tested, processed, and stored at cryogenic temperatures of around -185°C in
specialized freezers or storage tanks. Many banks process cord blood within 48
hours of collection and test it for quality, viability of stem cells, and
presence of any infectious diseases. Processed units meeting all criteria are
then placed in long term storage and available for future transplantation
needs. Cord blood is preserved for at least 20 years or more depending on the
banking facility's policies.
Factors Impacting Cord Blood Banking Services
There are various factors families need to consider when deciding between
public vs private cord blood banking or whether to bank at all. The primary
factors are anticipated need, cost, genetic diseases in the family, mixed
family racial heritage, and long term storage access and costs. Families at
higher risk for certain genetic conditions have greater reason to privately
bank. Those without known risks can evaluate public banking's benefits versus
the initial private storage fees and ongoing annual costs which average
hundreds per year. Proper understanding of these factors helps families make
informed choices regarding umbilical cord blood banking.
Conditions Potentially Treatable with Cord Blood Stem Cells
As medical research advances, more diseases are becoming treatable with stem
cells from umbilical cord blood. Currently, cord blood transplants are
routinely used to treat over 80 conditions including various blood cancers like
leukemia, lymphoma, and myelodysplastic syndrome. Researchers are also
investigating its potential to treat cerebral palsy, autism, traumatic brain
injuries, diabetes, heart disease, and neurodegenerative diseases. Clinical
trials using gene-edited cord blood stem cells hold promise for new genetic
therapies. Though risk of non-engraftment and graft-versus-host disease exist,
cord blood transplants involve less complications than traditional bone marrow
or peripheral blood stem cells. This expanding scope of applications highlights
cord blood banking's value as a potential lifesaving medical resource.
Logistics of Using Banked Cord Blood for Treatment
In the event cord blood stored at a bank is needed for transplantation, the
process typically starts with obtaining a referral from a blood cancer
specialist or the treating physician overseeing the condition. Stem cells from
the bank are then requested to be sent to the transplant center's blood bank.
The transplant team performs HLA tissue typing to match the cord blood sample
to the patient. If a suitable 6/6 HLA match is found, the cord blood unit is
shipped overnight on dry ice in specialized shipping containers. At the
hospital, the cord blood stem cells are infused into the patient after
chemotherapy or radiation to prepare them for engraftment and stem cell
regeneration. Cord blood transplants are usually non-invasive and do not
require a surgery. Post-transplant medical follow-up continues for months to
monitor and support engraftment and recovery. Provided there are no
complications, long term benefits accrue from these life-saving stem cell
infusions.
Cost Comparison of Cord Blood Banking Services Options
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